NEWS
JANUARY 2023
The Neurotech&Pizza seminars are back in 2023!
Alberto Lombardini brilliantly introduced us to JEDI-2P, a faster, brighter and more sensitive sensor for brain electrical activity
Great paper can be found here: https://www.cell.com/cell/pdf/S0092-8674(22)00916-3.pdf
DECEMBER 2022
New methods to accelerate 3D fluorescence imaging by Loic Le Goff from Institut Fresnel (Mosaic team, Aix Marseille Univ).
Intense discussion, new collaborations, and the promise to meet again soon...
Total success!
NOVEMBER 2022
Max presents the Neurotech Center at the 9-12 Recherche-Industrie Meeting.
Neurotech Centers are flourishing all around the world. Now Aix Marseille University has its own at INT!
Thank you Carnot Star for organizing this great event !
OCTOBER 2022
Inspiring #neurotech story by Frederic Ambroggi from Laboratoire de Neurosciences Cognitives (LNC, Aix Marseille Univ).
What do we need as Integrative Neuroscientists?
Record. Manipulate. Small. Wireless.
SEPTEMBER 2022
Wonderful talks at the Neurotech session of INT 10 Years Anniversary Symposium #XINT !!
Many thanks to our great speakers Tim Harris (HHMI Janelia Farm), Diego Ghezzi (EPFL) and Francesca Santoro (Aachen Univ) for presenting their cool toys and sharing their latest projects with us!
JUNE 2022
This month at the Neurotech/Pizza seminar, we learned about brain-on-chips and mmultiplexed microfluidic systems with the talented engineer and PhD candidate Maxime Poinsot (INT, Aix Marseille Univ) 🧠 🔬⚙️
MAY 2022
Another great neurotech seminar by Maya Williams (INT, Aix Marseille Univ) about calcium recordings using fiber photometry in freely moving rats ⚡️ 🧠 🐀
APRIL 2022
Neurotech seminars go next level with free food and drinks!
Nicolas Wanaverbecq (INT, Aix Marseille Univ) and David Moreau (Mines St Etienne) talk about flexible, implantable electro-optical devices for spinal cord recordings.
Rocket science as usual 🚀
APRIL 2022
Nobel Prize winner Ardem Patapoutian explaining the sense of touch in the beautiful Palais du Pharo in Marseille.
During his lecture, Pr Patapoutian invited Dr Bertand Coste (LNC, Aix Marseille Univ) to come to the stage to offer him one replica of his Nobel Prize medal. A very inspirational moment!
MARCH 2022
How to combine science, fun and beauty in one piece of work ?
Another great collaboration with Benoit Charlot (IES, Univ Montpellier) to induce waves of electrical activity in neuronal cultures.
MARCH 2022
Construction is looking good !
The new space for the NeuroTech Center is almost ready... Can't wait to move in for another great adventure with SONIC, NeuroBioTools and Rod's new NET team !!
Moving planned for July... Tic-Tac Tic-Tac
JANUARY 2022
"The Art of Science" exhibition at Galerie Le Pangolin on the beautiful Corniche of Marseille ended with a debate about the Artistic approach of Science.
Thank you NeuroMarseille for this great and successful adventure. Hope to see you next year for the second edition !
More details 👉 here 👈
DECEMBER 2021
Max talks about the RAIL Project at the 11th Neurobinar edition of NeuroMarseille.
Watch the full video on Youtube 👉 here 👈
NOVEMBER 2021
Great news!! 🥳 🥳
Maxime is awarded an ANRT CIFRE contract! He will start his PhD in the lab in collaboration with Fluigent.
Fluigent is a company specializing in the development and production of advanced microfluidic systems, with applications in various domains including cell biology, cancer research, particle studies, cell sorting, etc.. We are very happy to contribute to the development of a smart microfluidic system to model brain networks on a chip.
OCTOBER 2021
INT lab retreat at Carry-le-Rouet
Great science x (great people)² = Great times!
More photos 👉 here 👈
SEPTEMBER 2021
When Sciences meet Arts...
Our "Synaptic Constellation" picture is awarded at the Science & Art photo contest from Neuroschool Marseille 🎉🎉
Caption.
Confocal microscopy showing reconstructed synapses in a brain-on-a-chip device. Brain on a chip systems allow to reconstruct neuronal networks in a near-physiological environment using microfluidic compartmentalization of primary neuronal cultures. Here, synaptophysin (presynaptic marker, magenta) juxtaposes to PSD95 (postsynaptic marker, cyan) in an isolated microfluidic chambers enriched in synapses.
JULY 2021
Enjoying Thai food at l'Indécis before we all leave the lab for a well deserved summer break !
Aloha ! 🏖🏝⛱🏄♂️
It is our great pleasure to welcome Christoph Kellendonk from Columbia Univ, NY. Christoph will present his latest results on the role of thalamo-cortical projections in cognition and in schizophrenia.
Always nice to chat about science and life with you!
JULY 2021
Killing two birds with one stone: having lunch with the NeuroTech Center and surprising Rod with an impromptu BDay celebration !
Happy Birthday Rod 🎉🎉
JULY 2021
Davide Reato from Champalimaud Institute, Lisbon visits the NeuroTech Center. Davide will present his work on the role of cortical state in modulating perceptual decision making.
JUNE 2021
Benoit Charlot (IES, Montpellier) visits us at the NeuroTech Center.
As always Benoit amazed us with his crazy biotech approaches to explore cell functions!
DECEMBER 2020
Despite appearances, this is not a Masquerade Ball, but SONIC team's first Xmas party! (COVID-approved)
From Left to right: Max, Cynthia, Natalia, Eduardo, Elodie, Ana, Catherine, and Florence
NOVEMBER 2020
Champagne !!
We are happy to announce our fusion with Eduardo Gascon's team at the INT!
The fusion will lead to the creation of a new team entitled Social cogNItion and Connectomics (SoniC) where we will study and manipulate the neural circuits controlling social behaviors.
The synergy of the new team will allow to develop a multidisciplinary approach, using transcriptomics analyses, live cell imaging, virus-based connectomics, optogenetics, and behavioral phenotyping in mice and marmosets.
JULY 2020
After 5 years in Grenoble, we are officially moving to Marseille! Many thanks to all my collaborators at the GIN for the good moments and great work!
Excited for the future, and to move to the Neurotech Center of La Timone Medical campus. Welcoming postdocs, techs, and students to study how adult brain circuits rewire during learning or when confronted to environmental changes.
Goodbye snowy mountains, hello turquoise sea !
JUNE 2020
After many twists and turns during this hectic COVID-19 period, Eve finally defends her thesis (though remotely) entitled “Régulation du transport axonal par l’activité neuronale : Implication pour le développement des réseaux neuronaux” Committee: Dr. Zsolt Lenkei (Paris), Dr. Xavier Nicol (Paris Univ), Dr. Christophe Leterrier (Aix-Marseille Univ), Dr. Annie Andrieux (President, Grenoble Alpes Univ), Pr. Frederic Saudou (Grenoble Alpes Univ), Dr. Maxim Cazorla (Grenoble Alpes Univ/Aix-Marseille Univ).
DECEMBER 2019
Our project on the molecular mechanisms of neural network remodeling in the adult brain (SARABANDE project) is awarded a National Agency Research Young Investigator grant (ANR-JCJC)
MAY 2019
We are at the 2019 NeuroFrance Meeting in Marseille
NOVEMBER 2018
Eve’s paper in Lab Chip is out!! “An integrated microfluidic/microelectrode array for the study of activity-dependent intracellular dynamics in neuronal networks” by Moutaux E, Charlot B, Genoux A, Saudou F, and Cazorla M
SEPTEMBER 2018
Eve and Max at the FENS Cajal Advanced Neuroscience Training Program in the Bordeaux Neurocampus
SEPTEMBER 2018
Julien defends his Master at Grenoble INP Phelma. Congrats !
SEPTEMBER 2018
Eve’s paper in Scientific Reports is out!! “Neuronal network maturation differently affects secretory vesicles and mitochondria transport in axons” by Moutaux E, Christaller, W, Scaramuzzino C, Genoux A, Charlot B, Cazorla M*, and Saudou F*
JULY 2018
Julie Anne defends her thesis entitled “Identification d’une forme phosphorylée de BDNF: un nouveau mécanisme de régulation de la plasticité synaptique et de la mémoire ?” Committee: Dr. Helene Marie (Nice Univ), Pr. Yves-Alain Barde (Cardiff Univ), Dr. Servane Tauszig-Delamasure (Lyon Univ), Dr. Peter Vanhoutte (Paris-Sorbonne Univ), Pr. Remy Sadoul (President, Grenoble Alpes Univ), Pr. Frederic Saudou (Grenoble Alpes Univ), Dr. Maxim Cazorla (Grenoble Alpes Univ)
JULY 2018
We are extremely pleased to welcome Prof Yves-Alain Barde from Cardiff University. Yves Alain will present his work on “Neurotrophins in development and diseases of the nervous system” before Julie Anne’s thesis defense
JUNE 2018
Rachel defends her Master thesis at Grenoble Alpes University. Congrats !
JANUARY 2018
Public media talk about our work ! Check out Le Monde (La maladie de Huntington mise en microtubes), 20 Minutes (Maladie de Huntington: Des chercheurs ont recréé le trouble cérébral sur une puce électronique), Sciences & Avenir (Une puce va permettre de mieux comprendre la maladie de Huntington) and Pour La Science (La microfluidique éclaire la maladie de Huntington).
JANUARY 2018
Amandine’s paper is out in Cell Reports!! “Reconstituting Corticostriatal Network on-a-Chip Reveals the Contribution of the Presynaptic Compartment to Huntington’s Disease” by Virlogeux A, Moutaux E, Christaller W, Genoux A, Bruyère J, Fino E, Charlot B, Cazorla M, Saudou F
NOVEMBER 2017
Eve and Max talk at the 2017 Neurofluidics meeting on the CEA Minatec Campus in Grenoble to present our latest development in brain-on-a-chip devices and microelectrode arrays
OCTOBER 2017
Max is presenting our work on “Brain-on-a-chip reconstruction of corticostriatal networks to study Huntington’s disease” at the CoEN Annual meeting (Centre d’Excellence sur les maladies Neurodégénératives) in Montpellier
SEPTEMBER 2017
Clementine defends her Master at Grenoble INP Phelma. Congrats !
MAY 2017
We are at the 2017 NeuroFrance Meeting in Bordeaux
MAY 2017
Julie and Max at the 2017 EMBO workshop on Cell biology of the neuron: Polarity, plasticity and regeneration in Heraklion, Crete
JANUARY 2017
Our ATK program for the development of positive allosteric modulators of TrkB is selected by SATT Conectus Alsace for a 3 year Development of Innovative Projects program !
SEPTEMBER 2016
Theo defends his Master at Grenoble INP Phelma. Congrats !
AUGUST 2016
Our collaborators Michel Verheij and Candice Contet from The Scripps Institute release their paper in J Neuroscience: “Systemic Delivery of a Brain-Penetrant TrkB Antagonist Reduces Cocaine Self-Administration and Normalizes TrkB Signaling in the Nucleus Accumbens and Prefrontal Cortex“. Congratulations !
MAY 2016
Ready to start a SATT Conectus Alsace Prematuration Program with our collaborator Didier Rognan (LIT, Strasbourg) ! The aim of the project is to establish the proof of concept for the development of positive allosteric modulators of TrkB
MARCH 2016
Eve defends her Master at Grenoble INP Phelma. Congrats !
FEBRUARY 2016
Dr Pierre Trifilieff (Bordeaux Neurocampus) visits us at the GIN and presents his work on “Dopamine D2 receptor signaling in reward processing: From heteromerization to modulation by membrane lipids” (and enjoys a good weekend of fresh powder!)
JUNE 2015
Our review in Movement Disorder is out !! “Balancing the basal ganglia circuitry: a possible new role for dopamine D2 receptors in health and disease” by Cazorla M, Kang UJ, Kellendonk C.
MAY 2015
We are at the 2015 NeuroFrance Meeting in Montpellier
MAY 2015
Mariya defends her Master at Grenoble Alpes University. Congrats !
MARCH 2015
Our collaborator Benoit Charlot (IES, Montpellier) visits us and presents his work entitled “Micro and nanotechnologies for life sciences : single molecule combing, microfluidics for neurosciences and infrared stimulation of action potential in neurons”
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JANUARY 2015
Joining the Grenoble Institute of Neuroscience in F. Saudou's Team "Intracellular Dynamics and Neurodegeneration" to study how neuronal activity controls axon remodeling in mature circuits. Specifically, we will explore how vesicular trafficking responds to electrical signals to address essential materials to active axonal branches, using high-resolution fast videomicroscopy in brain-on-a-chip devices.
